EXPRESSION OF ANDROGEN RECEPTOR IS NEGATIVELY REGULATED BY P53

Expression of Androgen Receptor Is Negatively Regulated By p53

Increased expression of androgen receptor (AR) in prostate cancer (PC) is associated with transition to androgen independence.Because the progression of PC to advanced stages is often associated with the loss of p53 function, we tested whether the p53 could regulate the expression of AR gene.Here we report that p53 negatively regulates the expressi

read more


Tendon pathology in patients with distal radius palmar locked plate: incidence and clinical outcome of their treatment.

Introduction: The aim of this paper is to report the incidence of tendon complications in patients with distal radius fractures treated with volar locking plates and the clinical results after plate removal.Material and Methods 992 patients with distal radial fracture treated with volar locking plates were retrosopectively reviewed.Cases with plate

read more

Applying systems approaches to stakeholder and community engagement and knowledge mobilisation in youth mental health system modelling

Abstract Background There is a significant push to change the trajectory of youth mental ill-health and suicide globally.Ensuring that young people have access to services that meet their individual needs and are easily accessible is a priority.Genuine stakeholder engagement in mental health system design is critical to ensure that system strengthe

read more

Deep-Deterministic Policy Gradient Based Multi-Resource Allocation in Edge-Cloud System: A Distributed Approach

Edge Cloud (EC) empowers the beyond 5G (B5G) wireless networks to cope with large-scale and real-time traffics of Internet-of-Things (IoT) by minimizing the latency and providing compute power at the edge of the network.Due to a limited amount of resources at the EC compared to the back-end cloud (BC), intelligent resource management techniques bec

read more